Transforming Growth Factor-β Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors

PURPOSE: Pancreatic ductal adenocarcinoma (PDAC) is lethal cancer whose primary tumor is characterized by dense composition of cancer cells, stromal cells and extracellular matrix (ECM) composed largely of collagen. Within the PDAC tumor microenvironment, activated pancreatic stellate cells (PSC) ar...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Kang, Ya’an, Roife, David, Lee, Yeonju, Lv, Hailong, Suzuki, Rei, Ling, Jianhua, Rios Perez, Mayrim V., Li, Xinqun, Dai, BingBing, Pratt, Michael, Truty, Mark J., Chatterjee, Deyali, Wang, Huamin, Thomas, Ryan M., Wang, Yu, Koay, Eugene J, Chiao, Paul J., Katz, Matthew H., Fleming, Jason B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127652/
https://ncbi.nlm.nih.gov/pubmed/27126993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2780
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados