Prolonged exposure to extracellular lumican restrains pancreatic adenocarcinoma growth

We previously demonstrated that pancreatic stellate cells within pancreatic ductal adenocarcinoma (PDAC) stroma secrete lumican and its presence is associated with prolonged survival of patients with localized PDAC. Here, we observed that extracellular lumican decreases PDAC tumour cell growth in xe...

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Publicat a:Oncogene
Autors principals: Li, X, Kang, Y, Roife, D, Lee, Y, Pratt, M, Perez, MR, Dai, B, Koay, EJ, Fleming, JB
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799806/
https://ncbi.nlm.nih.gov/pubmed/28534517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.125
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