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PTPN22 inhibition resets defective human central B cell tolerance
The 1858T protein tyrosine phosphatase nonreceptor type 22 (PTPN22 T) allele is one of the main risk factors associated with many autoimmune diseases and correlates with a defective removal of developing autoreactive B cells in humans. To determine whether inhibiting PTPN22 favors the elimination of...
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| 出版年: | Sci Immunol |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5127630/ https://ncbi.nlm.nih.gov/pubmed/27917411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aaf7153 |
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