Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model

The search for an HIV-1 cure has been greatly hindered by the presence of a viral reservoir that persists despite antiretroviral therapy (ART). Studies of HIV-1 latency in vivo are also complicated by the low proportion of latently infected cells in HIV-1 infected individuals. A number of models of...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: White, Cory H., Moesker, Bastiaan, Beliakova-Bethell, Nadejda, Martins, Laura J., Spina, Celsa A., Margolis, David M., Richman, Douglas D., Planelles, Vicente, Bosque, Alberto, Woelk, Christopher H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127598/
https://ncbi.nlm.nih.gov/pubmed/27898737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006026
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