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Long non-coding RNAs and latent HIV – A search for novel targets for latency reversal

The latent cellular reservoir of HIV is recognized as the major barrier to cure from HIV infection. Long non-coding RNAs (lncRNAs) are more tissue and cell type-specific than protein coding genes, and may represent targets of choice for HIV latency reversal. Using two in vitro primary T-cell models,...

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Publicat a:PLoS One
Autors principals: Trypsteen, Wim, White, Cory H., Mukim, Amey, Spina, Celsa A., De Spiegelaere, Ward, Lefever, Steve, Planelles, Vicente, Bosque, Alberto, Woelk, Christopher H., Vandekerckhove, Linos, Beliakova-Bethell, Nadejda
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844474/
https://ncbi.nlm.nih.gov/pubmed/31710657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224879
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