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Precise genome editing by homologous recombination

Simple and efficient methods are presented for creating precise modifications of the zebrafish genome. Edited alleles are generated by homologous recombination between the host genome and double-stranded DNA (dsDNA) donor molecules, stimulated by the induction of double-strand breaks at targeted loc...

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Bibliografiske detaljer
Udgivet i:Methods Cell Biol
Main Authors: Hoshijima, K., Jurynec, M.J., Grunwald, D.J.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127288/
https://ncbi.nlm.nih.gov/pubmed/27443923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mcb.2016.04.008
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