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Precise genome editing by homologous recombination

Simple and efficient methods are presented for creating precise modifications of the zebrafish genome. Edited alleles are generated by homologous recombination between the host genome and double-stranded DNA (dsDNA) donor molecules, stimulated by the induction of double-strand breaks at targeted loc...

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Détails bibliographiques
Publié dans:Methods Cell Biol
Auteurs principaux: Hoshijima, K., Jurynec, M.J., Grunwald, D.J.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127288/
https://ncbi.nlm.nih.gov/pubmed/27443923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mcb.2016.04.008
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