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Enhancement of Precise Gene Editing by the Association of Cas9 With Homologous Recombination Factors
The CRISPR-Cas9 system is used for genome editing in mammalian cells by introducing double-strand breaks (DSBs) which are predominantly repaired via non-homologous end joining (NHEJ) or to lesser extent by homology-directed repair (HDR). To enhance HDR for improving the introduction of precise genet...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2019-04-01
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| シリーズ: | Frontiers in Genetics |
| 主題: | |
| オンライン･アクセス: | https://www.frontiersin.org/article/10.3389/fgene.2019.00365/full |
| タグ: |
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