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HIV-1 Glycan Density Drives the Persistence of the Mannose Patch within an Infected Individual
The HIV envelope glycoprotein (Env) is extensively modified with host-derived N-linked glycans. The high density of glycosylation on the viral spike limits enzymatic processing, resulting in numerous underprocessed oligomannose-type glycans. This extensive glycosylation not only shields conserved re...
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| Veröffentlicht in: | J Virol |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5126371/ https://ncbi.nlm.nih.gov/pubmed/27707925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01542-16 |
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