A unified molecular mechanism for the regulation of acetyl-CoA carboxylase by phosphorylation

Acetyl-CoA carboxylases (ACCs) are crucial metabolic enzymes and attractive targets for drug discovery. Eukaryotic acetyl-CoA carboxylases are 250 kDa single-chain, multi-domain enzymes and function as dimers and higher oligomers. Their catalytic activity is tightly regulated by phosphorylation and...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cell Discov
Auteurs principaux: Wei, Jia, Zhang, Yixiao, Yu, Tai-Yuan, Sadre-Bazzaz, Kianoush, Rudolph, Michael J, Amodeo, Gabriele A, Symington, Lorraine S, Walz, Thomas, Tong, Liang
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126230/
https://ncbi.nlm.nih.gov/pubmed/27990296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2016.44
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires