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Acetyl-CoA Carboxylase Regulates Global Histone Acetylation

Histone acetylation depends on intermediary metabolism for supplying acetyl-CoA in the nucleocytosolic compartment. However, because nucleocytosolic acetyl-CoA is also used for de novo synthesis of fatty acids, histone acetylation and synthesis of fatty acids compete for the same acetyl-CoA pool. Th...

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Bibliografski detalji
Glavni autori: Galdieri, Luciano, Vancura, Ales
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390662/
https://ncbi.nlm.nih.gov/pubmed/22580297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.380519
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