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Histone hypoacetylation-activated genes are repressed by acetyl-CoA- and chromatin-mediated mechanism

Transcriptional activation is typically associated with increased acetylation of promoter histones. However, this paradigm does not apply to transcriptional activation of all genes. In this study we have characterized a group of genes that are repressed by histone acetylation. These histone hypoacet...

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Detalhes bibliográficos
Main Authors: Mehrotra, Swati, Galdieri, Luciano, Zhang, Tiantian, Zhang, Man, Pemberton, Lucy F., Vancura, Ales
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136683/
https://ncbi.nlm.nih.gov/pubmed/24907648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2014.05.029
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