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Histone hypoacetylation-activated genes are repressed by acetyl-CoA- and chromatin-mediated mechanism

Transcriptional activation is typically associated with increased acetylation of promoter histones. However, this paradigm does not apply to transcriptional activation of all genes. In this study we have characterized a group of genes that are repressed by histone acetylation. These histone hypoacet...

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Bibliographic Details
Main Authors: Mehrotra, Swati, Galdieri, Luciano, Zhang, Tiantian, Zhang, Man, Pemberton, Lucy F., Vancura, Ales
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136683/
https://ncbi.nlm.nih.gov/pubmed/24907648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2014.05.029
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