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Histone hypoacetylation-activated genes are repressed by acetyl-CoA- and chromatin-mediated mechanism

Transcriptional activation is typically associated with increased acetylation of promoter histones. However, this paradigm does not apply to transcriptional activation of all genes. In this study we have characterized a group of genes that are repressed by histone acetylation. These histone hypoacet...

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Библиографические подробности
Главные авторы: Mehrotra, Swati, Galdieri, Luciano, Zhang, Tiantian, Zhang, Man, Pemberton, Lucy F., Vancura, Ales
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136683/
https://ncbi.nlm.nih.gov/pubmed/24907648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2014.05.029
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