A unified molecular mechanism for the regulation of acetyl-CoA carboxylase by phosphorylation

Acetyl-CoA carboxylases (ACCs) are crucial metabolic enzymes and attractive targets for drug discovery. Eukaryotic acetyl-CoA carboxylases are 250 kDa single-chain, multi-domain enzymes and function as dimers and higher oligomers. Their catalytic activity is tightly regulated by phosphorylation and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Discov
Egile Nagusiak: Wei, Jia, Zhang, Yixiao, Yu, Tai-Yuan, Sadre-Bazzaz, Kianoush, Rudolph, Michael J, Amodeo, Gabriele A, Symington, Lorraine S, Walz, Thomas, Tong, Liang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126230/
https://ncbi.nlm.nih.gov/pubmed/27990296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2016.44
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