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A unified molecular mechanism for the regulation of acetyl-CoA carboxylase by phosphorylation
Acetyl-CoA carboxylases (ACCs) are crucial metabolic enzymes and attractive targets for drug discovery. Eukaryotic acetyl-CoA carboxylases are 250 kDa single-chain, multi-domain enzymes and function as dimers and higher oligomers. Their catalytic activity is tightly regulated by phosphorylation and...
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| Vydáno v: | Cell Discov |
|---|---|
| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5126230/ https://ncbi.nlm.nih.gov/pubmed/27990296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2016.44 |
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