The aryl hydrocarbon receptor mediates the chemopreventive effect of indole-3-carbinol in an inflammation-associated colorectal tumorigenesis model

OBJECTIVE: To determine the role of the aryl hydrocarbon receptor (AHR) in colitis-associated colorectal tumorigenesis. SUMMARY BACKGROUND DATA: Colorectal cancer (CRC) is the third most commonly diagnosed cancer in both men and women in United States. Chronic intestinal inflammation increases the r...

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Vydáno v:Ann Surg
Hlavní autoři: Díaz-Díaz, Carol J., Ronnekleiv-Kelly, Sean M., Nukaya, Manabu, Geiger, Peter G., Hecht, Stephen S., Balbo, Silvia, Megna, Bryant W., Carney, Patrick R., Bradfield, Christopher A., Kennedy, Gregory D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125557/
https://ncbi.nlm.nih.gov/pubmed/27433903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SLA.0000000000001874
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