The Aryl Hydrocarbon Receptor as an Antitumor Target of Synthetic Curcuminoids in Colorectal Cancer

BACKGROUND: Curcumin has proven to be a potent antitumor agent in both preclinical and clinical models of colorectal cancer (CRC). It has also been identified as a ligand of the transcription factor known as the aryl hydrocarbon receptor (AHR). Our lab has identified the AHR as a mechanism which con...

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Detalhes bibliográficos
Publicado no:J Surg Res
Main Authors: Megna, Bryant W., Carney, Patrick R., Depke, Mitchell G., Nukaya, Manabu, McNally, James, Larson, Lesley, Rosengren, Rhonda J., Kennedy, Gregory D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467456/
https://ncbi.nlm.nih.gov/pubmed/28601309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2017.02.010
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