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Insulated neighborhoods: structural and functional units of mammalian gene control

Understanding how transcriptional enhancers control over 20,000 protein-coding genes to maintain cell type-specific gene expression programs in all human cells is a fundamental challenge in regulatory biology. Recent studies suggest that gene regulatory elements and their target genes generally occu...

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書目詳細資料
發表在:Cell
Main Authors: Hnisz, Denes, Day, Daniel S., Young, Richard A.
格式: Artigo
語言:Inglês
出版: 2016
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125522/
https://ncbi.nlm.nih.gov/pubmed/27863240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.10.024
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