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Peptide probes reveal a hydrophobic steric ratchet in the anthrax toxin protective antigen translocase
Anthrax toxin is a tripartite virulence factor produced by Bacillus anthracis during infection. Under acidic endosomal pH conditions, the toxin's protective antigen (PA) component forms a transmembrane channel in host cells. The PA channel then translocates its two enzyme components, lethal fac...
Enregistré dans:
| Publié dans: | J Mol Biol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5125378/ https://ncbi.nlm.nih.gov/pubmed/26363343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.09.007 |
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