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Electrostatic Ratchet in the Protective Antigen Channel Promotes Anthrax Toxin Translocation

Central to the power-stroke and Brownian-ratchet mechanisms of protein translocation is the process through which nonequilibrium fluctuations are rectified or ratcheted by the molecular motor to transport substrate proteins along a specific axis. We investigated the ratchet mechanism using anthrax t...

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Detalhes bibliográficos
Main Authors: Wynia-Smith, Sarah L., Brown, Michael J., Chirichella, Gina, Kemalyan, Gigi, Krantz, Bryan A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527960/
https://ncbi.nlm.nih.gov/pubmed/23115233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.419598
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