Loading...

6β-N-Heterocyclic Substituted Naltrexamine Derivative BNAP: A Peripherally Selective Mixed MOR/KOR Ligand

The 6β-N-heterocyclic naltrexamine derivative, NAP, has been demonstrated to be a peripherally selective mu opioid receptor modulator. To further improve peripheral selectivity of this highly potent ligand, its pyridal ring was quaterinized with benzyl bromide to produce BNAP. In radioligand binding...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:ACS Chem Neurosci
Main Authors: Williams, Dwight A., Zheng, Yi, David, Bethany G., Yuan, Yunyun, Zaidi, Saheem A., Stevens, David L., Scoggins, Krista L., Selley, Dana E., Dewey, William L., Akbarali, Hamid I., Zhang, Yan
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125022/
https://ncbi.nlm.nih.gov/pubmed/27269866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.6b00075
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!