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Inhibition of autophagy with bafilomycin and chloroquine decreases mitochondrial quality and bioenergetic function in primary neurons

Autophagy is an important cell recycling program responsible for the clearance of damaged or long-lived proteins and organelles. Pharmacological modulators of this pathway have been extensively utilized in a wide range of basic research and pre-clinical studies. Bafilomycin A1 and chloroquine are co...

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Bibliografische gegevens
Gepubliceerd in:Redox Biol
Hoofdauteurs: Redmann, Matthew, Benavides, Gloria A., Berryhill, Taylor F., Wani, Willayat Y., Ouyang, Xiaosen, Johnson, Michelle S., Ravi, Saranya, Barnes, Stephen, Darley-Usmar, Victor M., Zhang, Jianhua
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124357/
https://ncbi.nlm.nih.gov/pubmed/27889640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.11.004
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