Inhibition of autophagy with bafilomycin and chloroquine decreases mitochondrial quality and bioenergetic function in primary neurons

Autophagy is an important cell recycling program responsible for the clearance of damaged or long-lived proteins and organelles. Pharmacological modulators of this pathway have been extensively utilized in a wide range of basic research and pre-clinical studies. Bafilomycin A1 and chloroquine are co...

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Vydáno v:Redox Biol
Hlavní autoři: Redmann, Matthew, Benavides, Gloria A., Berryhill, Taylor F., Wani, Willayat Y., Ouyang, Xiaosen, Johnson, Michelle S., Ravi, Saranya, Barnes, Stephen, Darley-Usmar, Victor M., Zhang, Jianhua
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124357/
https://ncbi.nlm.nih.gov/pubmed/27889640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.11.004
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