Inhibition of autophagy with bafilomycin and chloroquine decreases mitochondrial quality and bioenergetic function in primary neurons

Autophagy is an important cell recycling program responsible for the clearance of damaged or long-lived proteins and organelles. Pharmacological modulators of this pathway have been extensively utilized in a wide range of basic research and pre-clinical studies. Bafilomycin A1 and chloroquine are co...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Redmann, Matthew, Benavides, Gloria A., Berryhill, Taylor F., Wani, Willayat Y., Ouyang, Xiaosen, Johnson, Michelle S., Ravi, Saranya, Barnes, Stephen, Darley-Usmar, Victor M., Zhang, Jianhua
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124357/
https://ncbi.nlm.nih.gov/pubmed/27889640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.11.004
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