Single-molecule imaging reveals that Rad4 (XPC) employs a dynamic DNA damage recognition process

Nucleotide excision repair (NER) is an evolutionarily conserved mechanism that processes helix-destabilizing and/or -distorting DNA lesions, such as UV-induced photoproducts. Here, we investigate the dynamic protein-DNA interactions during the damage recognition step using single-molecule fluorescen...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Kong, Muwen, Liu, Lili, Chen, Xuejing, Driscoll, Katherine I., Mao, Peng, Böhm, Stefanie, Kad, Neil M., Watkins, Simon C., Bernstein, Kara A., Wyrick, John J., Min, Jung-Hyun, Van Houten, Bennett
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123691/
https://ncbi.nlm.nih.gov/pubmed/27720644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.09.005
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