Core Binding Factor β Protects HIV, Type 1 Accessory Protein Viral Infectivity Factor from MDM2-mediated Degradation

HIV, type 1 overcomes host restriction factor apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3) proteins by organizing an E3 ubiquitin ligase complex together with viral infectivity factor (Vif) and a host transcription cofactor core binding factor β (CBFβ). CBFβ is essenti...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Matsui, Yusuke, Shindo, Keisuke, Nagata, Kayoko, Yoshinaga, Noriyoshi, Shirakawa, Kotaro, Kobayashi, Masayuki, Takaori-Kondo, Akifumi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2016
Onderwerpen:
Microbiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122761/
https://ncbi.nlm.nih.gov/pubmed/27758855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.734673
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