p53 predominantly regulates IL-6 production and suppresses synovial inflammation in fibroblast-like synoviocytes and adjuvant-induced arthritis

BACKGROUND: Dominant-negative somatic mutations of p53 has been identified in the synovium of patients with rheumatoid arthritis (RA), in which interleukin (IL)-6 has been established as a pivotal inflammatory cytokine. The aim of this study was to clarify the significance of p53 in the longstanding...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Arthritis Res Ther
Main Authors: Zhang, Ting, Li, Huihua, Shi, Juan, Li, Sha, Li, Muyuan, Zhang, Lei, Zheng, Leting, Zheng, Dexian, Tang, Fulin, Zhang, Xuan, Zhang, Fengchun, You, Xin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121977/
https://ncbi.nlm.nih.gov/pubmed/27881147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1161-4
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker