Introduction of neutralizing immunogenicity index to the rational design of MERS coronavirus subunit vaccines

Viral subunit vaccines often contain immunodominant non-neutralizing epitopes that divert host immune responses. These epitopes should be eliminated in vaccine design, but there is no reliable method for evaluating an epitope's capacity to elicit neutralizing immune responses. Here we introduce...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Du, Lanying, Tai, Wanbo, Yang, Yang, Zhao, Guangyu, Zhu, Qing, Sun, Shihui, Liu, Chang, Tao, Xinrong, Tseng, Chien-Te K., Perlman, Stanley, Jiang, Shibo, Zhou, Yusen, Li, Fang
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121417/
https://ncbi.nlm.nih.gov/pubmed/27874853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13473
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