Searching for an ideal vaccine candidate among different MERS coronavirus receptor-binding fragments—The importance of immunofocusing in subunit vaccine design

The newly emerged Middle East respiratory syndrome coronavirus (MERS-CoV) is currently spreading among humans, making development of effective MERS vaccines a high priority. A defined receptor-binding domain (RBD) in MERS-CoV spike protein can potentially serve as a subunit vaccine candidate against...

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Detalhes bibliográficos
Main Authors: Ma, Cuiqing, Wang, Lili, Tao, Xinrong, Zhang, Naru, Yang, Yang, Tseng, Chien-Te K, Li, Fang, Zhou, Yusen, Jiang, Shibo, Du, Lanying
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194190/
https://ncbi.nlm.nih.gov/pubmed/25240756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.08.086
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