A Truncated Receptor-Binding Domain of MERS-CoV Spike Protein Potently Inhibits MERS-CoV Infection and Induces Strong Neutralizing Antibody Responses: Implication for Developing Therapeutics and Vaccines

An emerging respiratory infectious disease with high mortality, Middle East respiratory syndrome (MERS), is caused by a novel coronavirus (MERS-CoV). It was first reported in 2012 in Saudi Arabia and has now spread to eight countries. Development of effective therapeutics and vaccines is crucial to...

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Hlavní autoři: Du, Lanying, Kou, Zhihua, Ma, Cuiqing, Tao, Xinrong, Wang, Lili, Zhao, Guangyu, Chen, Yaoqing, Yu, Fei, Tseng, Chien-Te K., Zhou, Yusen, Jiang, Shibo
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852489/
https://ncbi.nlm.nih.gov/pubmed/24324708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081587
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