NF1 is a direct G protein effector essential for opioid signaling to Ras in the striatum

It is well recognized that, GPCRs can activate Ras-regulated kinase pathways to produce lasting changes in neuronal function. Mechanisms by which GPCRs transduce these signals and their relevance to brain disorders are not well understood. Here we identified a major Ras regulator, neurofibromin 1 (N...

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Detalhes bibliográficos
Publicado no:Curr Biol
Main Authors: Xie, Keqiang, Colgan, Lesley A., Dao, Maria T., Muntean, Brian S., Sutton, Laurie P., Orlandi, Cesare, Boye, Sanford L., Boye, Shannon E., Shih, Chien-Cheng, Li, Yuqing, Xu, Baoji, Smith, Roy G., Yasuda, Ryohei, Martemyanov, Kirill A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121064/
https://ncbi.nlm.nih.gov/pubmed/27773571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2016.09.010
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