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RGS7 regulates reward behavior by controlling opioid signaling in the striatum

BACKGROUND: Morphine mediates its euphoric and analgesic effects by acting on the μ-opioid receptor (MOR). MOR belongs to the family of G protein coupled receptors, whose signaling efficiency is controlled by the Regulator of G protein Signaling (RGS) proteins. Our understanding of the molecular div...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Sutton, Laurie P., Ostrovskaya, Olga, Dao, Maria, Xie, Keqiang, Orlandi, Cesare, Smith, Roy, Wee, Sunmee, Martemyanov, Kirill A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753143/
https://ncbi.nlm.nih.gov/pubmed/26364547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.07.026
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