Inhibitory Signaling to Ion Channels in Hippocampal Neurons Is Differentially Regulated by Alternative Macromolecular Complexes of RGS7

The neuromodulatory effects of GABA on pyramidal neurons are mediated by GABA(B) receptors (GABA(B)Rs) that signal via a conserved G-protein-coupled pathway. Two prominent effectors regulated by GABA(B)Rs include G-protein inwardly rectifying K(+) (GIRK) and P/Q/N type voltage-gated Ca(2+) (Ca(V)2)...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ostrovskaya, Olga I., Orlandi, Cesare, Fajardo-Serrano, Ana, Young, Samuel M., Lujan, Rafael, Martemyanov, Kirill A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234300/
https://ncbi.nlm.nih.gov/pubmed/30315127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1378-18.2018
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