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RGS7/Gβ5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABA(B)R-GIRK signaling

In the hippocampus, the inhibitory neurotransmitter GABA shapes the activity of the output pyramidal neurons and plays important role in cognition. Most of its inhibitory effects are mediated by signaling from GABAB receptor to the G protein-gated Inwardly-rectifying K+ (GIRK) channels. Here, we sho...

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Detalhes bibliográficos
Main Authors: Ostrovskaya, Olga, Xie, Keqiang, Masuho, Ikuo, Fajardo-Serrano, Ana, Lujan, Rafael, Wickman, Kevin, Martemyanov, Kirill A
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988575/
https://ncbi.nlm.nih.gov/pubmed/24755289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02053
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