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Medullary Thymic Epithelial Cells and CD8α(+) Dendritic Cells coordinately regulate central tolerance but CD8α(+) cells are Dispensable for Thymic Regulatory T cell production
In the thymus, antigen presenting cells (APCs) namely, medullary thymic epithelial cells (mTECs) and thymic dendritic cells (tDCs) regulate T cell tolerance through elimination of autoreactive T cells and production of thymic T regulatory (tTreg) cells. How the different APCs in the thymus share the...
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| Yayımlandı: | J Autoimmun |
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| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5121015/ https://ncbi.nlm.nih.gov/pubmed/27543048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2016.08.002 |
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