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Medullary Thymic Epithelial Cells and CD8α(+) Dendritic Cells coordinately regulate central tolerance but CD8α(+) cells are Dispensable for Thymic Regulatory T cell production
In the thymus, antigen presenting cells (APCs) namely, medullary thymic epithelial cells (mTECs) and thymic dendritic cells (tDCs) regulate T cell tolerance through elimination of autoreactive T cells and production of thymic T regulatory (tTreg) cells. How the different APCs in the thymus share the...
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| Publicat a: | J Autoimmun |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5121015/ https://ncbi.nlm.nih.gov/pubmed/27543048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2016.08.002 |
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