Alternative BCG delivery strategies improve protection against Mycobacterium tuberculosis in non-human primates: Protection associated with mycobacterial antigen-specific CD4 effector memory T-cell populations

Intradermal (ID) BCG injection provides incomplete protection against TB in humans and experimental models. Alternative BCG vaccination strategies may improve protection in model species, including rhesus macaques. This study compares the immunogenicity and efficacy of BCG administered by ID and int...

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Detalhes bibliográficos
Publicado no:Tuberculosis (Edinb)
Main Authors: Sharpe, S., White, A., Sarfas, C., Sibley, L., Gleeson, F., McIntyre, A., Basaraba, R., Clark, S., Hall, G., Rayner, E., Williams, A., Marsh, P.D., Dennis, M.
Formato: Artigo
Idioma:Inglês
Publicado em: Churchill Livingstone 2016
Assuntos:
Model Systems
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120991/
https://ncbi.nlm.nih.gov/pubmed/27865390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2016.09.004
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