Alternative BCG delivery strategies improve protection against Mycobacterium tuberculosis in non-human primates: Protection associated with mycobacterial antigen-specific CD4 effector memory T-cell populations

Intradermal (ID) BCG injection provides incomplete protection against TB in humans and experimental models. Alternative BCG vaccination strategies may improve protection in model species, including rhesus macaques. This study compares the immunogenicity and efficacy of BCG administered by ID and int...

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Sparad:
Bibliografiska uppgifter
I publikationen:Tuberculosis (Edinb)
Huvudupphovsmän: Sharpe, S., White, A., Sarfas, C., Sibley, L., Gleeson, F., McIntyre, A., Basaraba, R., Clark, S., Hall, G., Rayner, E., Williams, A., Marsh, P.D., Dennis, M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Churchill Livingstone 2016
Ämnen:
Model Systems
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120991/
https://ncbi.nlm.nih.gov/pubmed/27865390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2016.09.004
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