Alternative BCG delivery strategies improve protection against Mycobacterium tuberculosis in non-human primates: Protection associated with mycobacterial antigen-specific CD4 effector memory T-cell populations

Intradermal (ID) BCG injection provides incomplete protection against TB in humans and experimental models. Alternative BCG vaccination strategies may improve protection in model species, including rhesus macaques. This study compares the immunogenicity and efficacy of BCG administered by ID and int...

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Publicat a:Tuberculosis (Edinb)
Autors principals: Sharpe, S., White, A., Sarfas, C., Sibley, L., Gleeson, F., McIntyre, A., Basaraba, R., Clark, S., Hall, G., Rayner, E., Williams, A., Marsh, P.D., Dennis, M.
Format: Artigo
Idioma:Inglês
Publicat: Churchill Livingstone 2016
Matèries:
Model Systems
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120991/
https://ncbi.nlm.nih.gov/pubmed/27865390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2016.09.004
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