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Genome-Scale Assessment of Age-Related DNA Methylation Changes in Mouse Spermatozoa

DNA methylation plays important roles in the production and functioning of spermatozoa. Recent studies have suggested that DNA methylation patterns in spermatozoa can change with age, but the regions susceptible to age-related methylation changes remain to be fully elucidated. In this study, we cond...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Kobayashi, Norio, Okae, Hiroaki, Hiura, Hitoshi, Chiba, Hatsune, Shirakata, Yoshiki, Hara, Kenshiro, Tanemura, Kentaro, Arima, Takahiro
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120852/
https://ncbi.nlm.nih.gov/pubmed/27880848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167127
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