Genome-Wide Analysis of DNA Methylation Dynamics during Early Human Development

DNA methylation is globally reprogrammed during mammalian preimplantation development, which is critical for normal development. Recent reduced representation bisulfite sequencing (RRBS) studies suggest that the methylome dynamics are essentially conserved between human and mouse early embryos. RRBS...

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Bibliographic Details
Published in:PLoS Genet
Main Authors: Okae, Hiroaki, Chiba, Hatsune, Hiura, Hitoshi, Hamada, Hirotaka, Sato, Akiko, Utsunomiya, Takafumi, Kikuchi, Hiroyuki, Yoshida, Hiroaki, Tanaka, Atsushi, Suyama, Mikita, Arima, Takahiro
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263407/
https://ncbi.nlm.nih.gov/pubmed/25501653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004868
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