Genome-Wide Analysis of DNA Methylation Dynamics during Early Human Development

DNA methylation is globally reprogrammed during mammalian preimplantation development, which is critical for normal development. Recent reduced representation bisulfite sequencing (RRBS) studies suggest that the methylome dynamics are essentially conserved between human and mouse early embryos. RRBS...

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Dettagli Bibliografici
Pubblicato in:PLoS Genet
Autori principali: Okae, Hiroaki, Chiba, Hatsune, Hiura, Hitoshi, Hamada, Hirotaka, Sato, Akiko, Utsunomiya, Takafumi, Kikuchi, Hiroyuki, Yoshida, Hiroaki, Tanaka, Atsushi, Suyama, Mikita, Arima, Takahiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263407/
https://ncbi.nlm.nih.gov/pubmed/25501653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004868
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