Allele-Specific Methylome and Transcriptome Analysis Reveals Widespread Imprinting in the Human Placenta

DNA methylation is globally reprogrammed after fertilization, and as a result, the parental genomes have similar DNA-methylation profiles after implantation except at the germline differentially methylated regions (gDMRs). We and others have previously shown that human blastocysts might contain thou...

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Detalhes bibliográficos
Publicado no:Am J Hum Genet
Main Authors: Hamada, Hirotaka, Okae, Hiroaki, Toh, Hidehiro, Chiba, Hatsune, Hiura, Hitoshi, Shirane, Kenjiro, Sato, Tetsuya, Suyama, Mikita, Yaegashi, Nobuo, Sasaki, Hiroyuki, Arima, Takahiro
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097938/
https://ncbi.nlm.nih.gov/pubmed/27843122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.08.021
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