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Genome-Scale Assessment of Age-Related DNA Methylation Changes in Mouse Spermatozoa

DNA methylation plays important roles in the production and functioning of spermatozoa. Recent studies have suggested that DNA methylation patterns in spermatozoa can change with age, but the regions susceptible to age-related methylation changes remain to be fully elucidated. In this study, we cond...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Kobayashi, Norio, Okae, Hiroaki, Hiura, Hitoshi, Chiba, Hatsune, Shirakata, Yoshiki, Hara, Kenshiro, Tanemura, Kentaro, Arima, Takahiro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120852/
https://ncbi.nlm.nih.gov/pubmed/27880848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167127
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