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Genome-Scale Assessment of Age-Related DNA Methylation Changes in Mouse Spermatozoa

DNA methylation plays important roles in the production and functioning of spermatozoa. Recent studies have suggested that DNA methylation patterns in spermatozoa can change with age, but the regions susceptible to age-related methylation changes remain to be fully elucidated. In this study, we cond...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kobayashi, Norio, Okae, Hiroaki, Hiura, Hitoshi, Chiba, Hatsune, Shirakata, Yoshiki, Hara, Kenshiro, Tanemura, Kentaro, Arima, Takahiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120852/
https://ncbi.nlm.nih.gov/pubmed/27880848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167127
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