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Neuronal Release of Cytokine IL-3 Triggered by Mechanosensitive Autostimulation of the P2X7 Receptor Is Neuroprotective

Mechanical strain due to increased pressure or swelling activates inflammatory responses in many neural systems. As cytokines and chemokine messengers lead to both pro-inflammatory and neuroprotective actions, understanding the signaling patterns triggered by mechanical stress may help improve overa...

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Pubblicato in:Front Cell Neurosci
Autori principali: Lim, Jason C., Lu, Wennan, Beckel, Jonathan M., Mitchell, Claire H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120082/
https://ncbi.nlm.nih.gov/pubmed/27932954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00270
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