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Neuronal Release of Cytokine IL-3 Triggered by Mechanosensitive Autostimulation of the P2X7 Receptor Is Neuroprotective

Mechanical strain due to increased pressure or swelling activates inflammatory responses in many neural systems. As cytokines and chemokine messengers lead to both pro-inflammatory and neuroprotective actions, understanding the signaling patterns triggered by mechanical stress may help improve overa...

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Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: Lim, Jason C., Lu, Wennan, Beckel, Jonathan M., Mitchell, Claire H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120082/
https://ncbi.nlm.nih.gov/pubmed/27932954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00270
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