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Pharmacodynamics of Ceftolozane Combined with Tazobactam against Enterobacteriaceae in a Neutropenic Mouse Thigh Model

Ceftolozane is a new broad-spectrum cephalosporin and is combined with tazobactam to broaden the activity of ceftolozane against strains producing extended-spectrum beta-lactamases (ESBLs). We determined the pharmacodynamics (PD) of the combination in the neutropenic mouse thigh model to determine t...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Melchers, M. J., Mavridou, E., van Mil, A. C., Lagarde, C., Mouton, J. W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119007/
https://ncbi.nlm.nih.gov/pubmed/27671063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01580-16
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