Pharmacodynamics of Ceftazidime and Avibactam in Neutropenic Mice with Thigh or Lung Infection

Avibactam is a new non-β-lactam β-lactamase inhibitor that shows promising restoration of ceftazidime activity against microorganisms producing Ambler class A extended-spectrum β-lactamases (ESBLs) and carbapenemases such as KPCs, class C β-lactamases (AmpC), and some class D enzymes. To determine o...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Berkhout, Johanna, Melchers, Maria J., van Mil, Anita C., Seyedmousavi, Seyedmojtaba, Lagarde, Claudia M., Schuck, Virna J., Nichols, Wright W., Mouton, Johan W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704241/
https://ncbi.nlm.nih.gov/pubmed/26525790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01269-15
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