A potential endophenotype for Alzheimer’s disease: cerebrospinal fluid clusterin

Genome-wide association studies have associated clusterin (CLU) variants with Alzheimer’s disease (AD). However the role of CLU on AD pathogenesis is not totally understood. We used CSF and plasma CLU levels as endophenotypes for genetic studies to understand the role of CLU in AD. CSF, but not plas...

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Vydáno v:Neurobiol Aging
Hlavní autoři: Deming, Yuetiva, Xia, Jian, Cai, Yefei, Lord, Jenny, Holmans, Peter, Bertelsen, Sarah, Holtzman, David, Morris, John C, Bales, Kelly, Pickering, Eve H, Kauwe, John, Goate, Alison, Cruchaga, Carlos
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118651/
https://ncbi.nlm.nih.gov/pubmed/26545630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.09.009
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