Ptau-Aβ(42) ratio as a continuous trait for biomarker discovery for early stage Alzheimer’s disease in multiplex immunoassay panels of Cerebrospinal fluid

BACKGROUND: Identification of the physiological changes that occur during the early stages of Alzheimer’s disease (AD) may provide critical insights for the diagnosis, prognosis and treatment of disease. Cerebrospinal fluid (CSF) biomarkers are a rich source of information that reflect the brain pro...

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Detalhes bibliográficos
Main Authors: Harari, Oscar, Cruchaga, Carlos, Kauwe, John S.K., Ainscough, Benjamin J., Bales, Kelly, Pickering, Eve H., Bertelsen, Sarah, Fagan, Anne M., Holtzman, David M., Morris, John C., Goate, Alison M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007142/
https://ncbi.nlm.nih.gov/pubmed/24548642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2013.11.032
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