A potential endophenotype for Alzheimer’s disease: cerebrospinal fluid clusterin

Genome-wide association studies have associated clusterin (CLU) variants with Alzheimer’s disease (AD). However the role of CLU on AD pathogenesis is not totally understood. We used CSF and plasma CLU levels as endophenotypes for genetic studies to understand the role of CLU in AD. CSF, but not plas...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Deming, Yuetiva, Xia, Jian, Cai, Yefei, Lord, Jenny, Holmans, Peter, Bertelsen, Sarah, Holtzman, David, Morris, John C, Bales, Kelly, Pickering, Eve H, Kauwe, John, Goate, Alison, Cruchaga, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118651/
https://ncbi.nlm.nih.gov/pubmed/26545630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.09.009
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